HumBO – Publications

Equipe

Vincent El Ghouzzi, DR, Directeur Scientifique

Manon Moussay, IR, Responsable Opérationnelle

Alexandra Albert, AI, Responsable Technique

Malgorzata Rak, CRCN, Responsable Scientifique Axe Métabolisme énergétique mitochondrial

Sophie Lebon, IR, Edition du Genome par CRISPR/Cas

Sandrine Passemard, PUPH, Interface clinique

Publications

• Albert A, Couture L, Piumi F, Lebon S, Gressens P, Coulpier M, Amara A, El Ghouzzi V*, Meertens L*. Oropouche virus infects human neural progenitor cells and alters the growth of brain organoids. iScience 2026, in press
• Farcy S, Albert A, Gressens P, Baffet A.D, El Ghouzzi V. Cortical Organoids to Model Microcephaly. Cells 2022, 11 (14):2135
• Passera S, Boccazzi M, Bokobza C, Faivre V, Mosca F, Van Steenwinckel J, Fumagalli M, Gressens P, Fleiss B. Therapeutical potential of stem cells for preterm infant brain damage: Can we move from the heterogeneity of preclinical and clinical studies to established therapeutics? Biochem. Pharmacol. 2021 Apr; 186:114461.
• Benlamara S, Aubry L, Fabregue J, Bénit P, Rustin P, Rak M. Distinctive Krebs cycle remodeling in iPSC-derived neural and mesenchymal stem cells. Biochem Biophys Res Commun. 2019 Apr 9;511(3):658-664.
• El Ghouzzi V, Bianchi FT, Molineris I, Mounce BC, Berto GE, Rak M, Lebon S, Aubry L, Tocco C, Gai M, Chiotto AMA, Sgrò F, Pallavicini G, Simon-Loriere E, Passemard S, Vignuzzi M, Gressens P, Di Cunto F.  ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly. Cell Death Dis. 2018 Nov 20;9(12):1155.
• Kumar M, Csaba Z, Peineau S, Srivastava R, Rasika S, Mani S, Gressens P, El Ghouzzi V. Endogenous cerebellar neurogenesis in adult mice with progressive ataxia. Ann Clin Transl Neurol. 2014 Dec;1(12):968-81.
• Srivastava R, Kumar M, Peineau S, Csaba Z, Mani S, Gressens P, El Ghouzzi V. Conditional induction of Math1 specifies embryonic stem cells to cerebellar granule neuron lineage and promotes differentiation into mature granule neurons. Stem Cells. 2013 Apr;31(4):652-65.
• Titomanlio L, Kavelaars A, Dalous J, Mani S, El Ghouzzi V, Heijnen C, Baud O, Gressens P. Stem cell therapy for neonatal brain injury: perspectives and challenges. Ann Neurol. 2011 Nov;70(5):698-712.
• Titomanlio L, Bouslama M, Le Verche V, Dalous J, Kaindl AM, Tsenkina Y, Lacaud A, Peineau S, El Ghouzzi V, Lelièvre V, Gressens P. Implanted neurosphere-derived precursors promote recovery after neonatal excitotoxic brain injury. Stem Cells Dev. 2011 May;20(5):865-79.